Osteology Resources and Tools For Bone and Joint Research

 

 

As a critical branch of anatomy and biology, osteology is the scientific study of bones and the skeletal system, encompassing their structure, function, development, and pathology. This field provides essential insights for understanding human movement, structural support, and various skeletal diseases.

Whether investigating bone marrow function or exploring skeletal structures, a comprehensive portfolio of osteology products is designed to support your research.

Explore our wide selection of osteology research tools

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The products provide precise, reliable resources, including models and tools for studying cartilage, synovium, and synovial fluid—essential components for understanding joint health and diseases.

Reach out to our technical support team for assistance in identifying, configuring, and sourcing the samples that best align with your scientific goals.

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                          Bone marrow   Skeletal system
     

cDNA

  • Reveals gene expression in blood and stem cells.

  • Helps identify unknown genes in hematopoiesis and immunity.

  • Provides insight into genein health and disease.

 

Osteoblasts

  • CDNA reflects gene expression.

  • Genomic DNA encodes essential bone-related genes.

  • RNA includes transcripts for proteins and transcription factors.

Genomic DNA

  • Encodes genes for blood cell production and immune response.

  • Its analysis aids diagnosis and therapy decisions in hematologic diseases

  • Helps identify inherited syndromes and disease risk in bone marrow.

 

Osteocytes

  • Genomic DNA contains genes essential for bone regulation and structure.

  • RNA defines a unique gene signature linked to bone remodeling.

  • cDNA reveals molecular programs controlling their network and function

Primary cells

  • CD34 marks hematopoietic stem cells in bone marrow.

  • Stromal cells create a supportive environment for blood cell growth.

  • Mesenchymal stem cells in bone marrow form bone, cartilage, and fat cells.

 

Skeletal muscle

  • CDNA shows active gene expression for muscle differentiation.

  • Genomic DNA contains genes vital for muscle growth and function.

  • RNA includes transcripts for proteins essential in contraction and repair.

RNA

  • Total RNA includes all RNA types in bone marrow cells for gene expression.

  • microRNAs regulate gene expression post-transcriptionally.

  • Mesenchymal stem cells in bone marrow form bone, cartilage, and fat cells.

 

Chondrocytes

  •  Are the main cells in cartilage, producing and maintaining its matrix.

  • Regulate cartilage repair and respond to mechanical and biochemical signals.

  • Synthesize collagen, proteoglycans, and enzymes critical for cartilage strength and flexibility.

Frozen tissue sections

  • Frozen bone marrow sections are fast to prepare and preserve cell structures well.

  • They keep proteins and antigens intact for accurate immunostaining.

  • Useful for quick diagnosis during surgery and molecular analyses.

 

Pulposus cells

  • Are found in the nucleus pulposus, the soft, gelatinous center of intervertebral discs.

  • Maintain disc flexibility and hydration.

  •  Thrive in a low-oxygen, nutrient-poor environment unique to the avascular intervertebral disc.

Paraffin tissue sections

  • Are thin, fixed slices for detailed study.

  • They preserve tissue well for long-term analysis.

  • Used to diagnose blood disorders with precise staining.

 

Synovial cells

  • Form the thin lining of joint cavities.

  • Consist mainly of synoviocytes.

  • Help maintain joint lubrication and cartilage nutrition.

 

Browse our wide range of osteology products and solutions

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