Ten-Eleven Translocation antibodies

Ten-Eleven Translocation antibodies

TET antibodies are immunoreagents designed to detect the Ten-Eleven Translocation (TET) family of dioxygenases, including TET1, TET2, and TET3. These enzymes catalyze the oxidation of 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC), initiating active DNA demethylation and regulating epigenetic processes involved in gene expression, stem cell maintenance, cellular differentiation, and development.

Antibody Types and Formats

TET antibodies are available for each member of the TET family in monoclonal, recombinant monoclonal, and polyclonal formats. TET1 antibodies are widely validated for Western blotting, immunoprecipitation, ELISA, chromatin immunoprecipitation, immunofluorescence, and immunocytochemistry. TET2 antibodies include rabbit recombinant monoclonal and polyclonal variants suitable for Western blotting, immunocytochemistry, immunohistochemistry, and ELISA, while TET3 antibodies are commonly validated for Western blotting and ELISA. 

Applications and Advantages

  • Epigenetic research: Enables the investigation of DNA demethylation pathways and hydroxymethylation dynamics mediated by TET enzymes.
  • Broad application range: Validated for Western blotting, immunoprecipitation, immunofluorescence, chromatin immunoprecipitation (ChIP), ELISA, immunocytochemistry, and immunohistochemistry.
  • Species compatibility: Most antibodies are developed against human TET proteins and exhibit confirmed cross-reactivity with mouse and rat samples. Specialized antibodies for Drosophila TET are also available for model organism studies.

Frequently Asked Questions (FAQ)

How can I quickly find a tet antibodies product?

To find a tet antibodies product, use the search function by name, product code, supplier, brand or sub-category. You can also browse the product families listed on the page to identify an available product code, an alternative or an equivalent product.

Does Oncomedics stock several product codes in the tet antibodies category?

Yes, Oncomedics distributes several product references in the tet antibodies category, sourced from specialist suppliers. Depending on the product family, references may vary in terms of format, packaging, brand, supplier, technical specifications or availability.

Can I request a quote for tet antibodies products?

Yes, you can request a quote for tet antibodies products from the product page or by contacting Oncomedics (info@oncomedics.com). To help us process your enquiry, please provide, where possible, the product name, catalogue reference, required quantity, the supplier or brand you are looking for, and the country of delivery.

How can I find out if a tet antibodies product is available to order?

The availability of a tet antibodies product depends on the product code, supplier, packaging and country of delivery. For up-to-date information, please check the product details page or contact Oncomedics with the product code or name of the product you are looking for.

What should I do if I cannot find the tet antibodies product I am looking for?

If the tet antibodies product you are looking for does not appear in the catalogue, please contact Oncomedics with the available information: product name, reference number, supplier, brand, format or packaging. The team will be able to search for the reference number within its network of suppliers or suggest an available alternative.

Are all tet antibodies products available under the same terms and conditions?

No. Ordering, delivery, storage and documentation conditions may vary depending on the product type, the supplier and the applicable regulations. Certain product codes may require specific approval, specialised transport, a safety data sheet or additional information prior to ordering.

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