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TET recombinant proteins

TET recombinant proteins

TET recombinant proteins are research-grade proteins derived mainly from TET1 and TET2, essential enzymes involved in DNA demethylation and epigenetic regulation. Produced as catalytic fragments or tagged recombinant proteins, they provide reliable tools for investigating enzyme activity, DNA methylation dynamics, and gene regulation in normal development and disease.

Characteristics

TET proteins are Fe(II)- and α-ketoglutarate-dependent dioxygenases that catalyze the oxidation of 5-methylcytosine. Recombinant proteins are commonly expressed in E. coli or baculovirus/Sf9 systems and frequently include His, FLAG, or GST tags to facilitate purification, detection, and biochemical analyses.

Applications

  • Enzyme assays: Measure TET catalytic activity and DNA demethylation efficiency.
  • Drug discovery: Screen inhibitors and evaluate selectivity toward epigenetic enzymes.
  • Epigenetic research: Investigate pluripotency, differentiation, cancer biology, and protein interactions.

Frequently Asked Questions (FAQ)

How can I quickly find a tet recombinant proteins product?

To find a tet recombinant proteins product, use the search function by name, product code, supplier, brand or sub-category. You can also browse the product families listed on the page to identify an available product code, an alternative or an equivalent product.

Does Oncomedics stock several product codes in the tet recombinant proteins category?

Yes, Oncomedics distributes several product references in the tet recombinant proteins category, sourced from specialist suppliers. Depending on the product family, references may vary in terms of format, packaging, brand, supplier, technical specifications or availability.

Can I request a quote for tet recombinant proteins products?

Yes, you can request a quote for tet recombinant proteins products from the product page or by contacting Oncomedics (info@oncomedics.com). To help us process your enquiry, please provide, where possible, the product name, catalogue reference, required quantity, the supplier or brand you are looking for, and the country of delivery.

How can I find out if a tet recombinant proteins product is available to order?

The availability of a tet recombinant proteins product depends on the product code, supplier, packaging and country of delivery. For up-to-date information, please check the product details page or contact Oncomedics with the product code or name of the product you are looking for.

What should I do if I cannot find the tet recombinant proteins product I am looking for?

If the tet recombinant proteins product you are looking for does not appear in the catalogue, please contact Oncomedics with the available information: product name, reference number, supplier, brand, format or packaging. The team will be able to search for the reference number within its network of suppliers or suggest an available alternative.

Are all tet recombinant proteins products available under the same terms and conditions?

No. Ordering, delivery, storage and documentation conditions may vary depending on the product type, the supplier and the applicable regulations. Certain product codes may require specific approval, specialised transport, a safety data sheet or additional information prior to ordering.

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