
Extraction and purification of genomic DNA - Difficult samples
Genomic DNA or gDNA is chromosomal DNA, in contrast to extra-chromosomal DNA such as plasmid DNA. Genomic DNA contains all the biological information to be passed on to the next generation. Most organisms have the same genomic DNA in all their cells, however only certain genes are active in each cell. Genomic DNA contains both so-called coding and non-coding regions, known as introns and exons. Introns are fragments of genes that do not have coding sequences. In general, introns are spliced or "deleted" from the RNA during the transcription process before protein synthesis. This is only possible in eukaryotes, prokaryotes are not able to splice introns. Exons are a necessary part of the coding system and are retained after splicing of introns.
Once isolated, gDNA can be used to create genomic libraries for DNA sequencing, fingerprinting, differentiation and other clinical and research applications.
Frequently Asked Questions (FAQ)
How can I quickly find a difficult samples product?
To find a difficult samples product, use the search function by name, product code, supplier, brand or sub-category. You can also browse the product families listed on the page to identify an available product code, an alternative or an equivalent product.
Does Oncomedics stock several product codes in the difficult samples category?
Yes, Oncomedics distributes several product references in the difficult samples category, sourced from specialist suppliers. Depending on the product family, references may vary in terms of format, packaging, brand, supplier, technical specifications or availability.
Can I request a quote for difficult samples products?
Yes, you can request a quote for difficult samples products from the product page or by contacting Oncomedics (info@oncomedics.com). To help us process your enquiry, please provide, where possible, the product name, catalogue reference, required quantity, the supplier or brand you are looking for, and the country of delivery.
How can I find out if a difficult samples product is available to order?
The availability of a difficult samples product depends on the product code, supplier, packaging and country of delivery. For up-to-date information, please check the product details page or contact Oncomedics with the product code or name of the product you are looking for.
What should I do if I cannot find the difficult samples product I am looking for?
If the difficult samples product you are looking for does not appear in the catalogue, please contact Oncomedics with the available information: product name, reference number, supplier, brand, format or packaging. The team will be able to search for the reference number within its network of suppliers or suggest an available alternative.
Are all difficult samples products available under the same terms and conditions?
No. Ordering, delivery, storage and documentation conditions may vary depending on the product type, the supplier and the applicable regulations. Certain product codes may require specific approval, specialised transport, a safety data sheet or additional information prior to ordering.
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